Summary of “Axolotl Genome Slowly Yields Secrets of Limb Regrowth”

Before the full genome of the axolotl was published, researchers who wanted insights into the animal’s molecular biology were mostly stuck looking at the protein and RNA products of axolotl genes.
Monaghan wants to know what changes in gene packaging and regulation turn a hand cell into a shoulder cell – that is, turn a regular axolotl into one with spaghetti arms.
Monaghan said his group is already using the new genome sequence as a reference to make genetically engineered salamanders with CRISPR, the revolutionary genome-editing technology that became available only a few years ago.
“No genome is ever complete. Even the human genome,” she said.
They’ll discuss how to use the genome sequences and other resources and will strategize about bringing new people into the field of axolotl research.
Monaghan is studying axolotl retinas to try to improve the outcomes of prospective stem cell therapies in aging human eyes.
Whited is studying whether the same proteins that are important in salamander limb regeneration could also be indicators of a good healing response after amputation in mice.
McCusker has studied how the tissue environment of a salamander’s regenerating limb controls the behavior of cells.

The orginal article.

Summary of “How to Avoid Going Broke After Making $650 Million”

Depp is now suing his business manager and his firm for negligence, breach of fiduciary duty and fraud.
So once again, I will lay out a simple set of rules that can help any recipient of new-found wealth avoid some of the most common errors, and maybe keep from going broke.
The most successful athletes and musicians have business managers who might handle the day-to-day chores while they are on the road working, but they must understand their own earnings, spending and investments.
Avoid debt: Living within your means should get easier as earnings rise.
If you spend six months shooting a film in Malaysia, you probably lack the time to monitor how much risk your hedge-fund managers are putting on.
Find an experienced pro other than your business manager – if you have one – to help manage this.
Understand what money is and what it isn’t: There is so much emotional baggage around money – especially the blind pursuit of it – that we often forget what it is.
Money is a tool that lets you accomplish specific things, whether paying for good health care, ensuring financial security, freeing you from stress and worry, or covering the costs of leisure and philanthropy.

The orginal article.

Summary of “12 fast-rising technologies to get ready for”

We asked members of the Young Entrepreneur Council which of our current technologies will likely be slated for widespread, innovative use within the near future.
While our focuses today may be on artificial intelligence, virtual reality and augmented reality, there are plenty of game-changing technology innovations at play in our tech-driven society.
The internet was designed at its core to be a decentralized system, but internet giants and many governments have warped the original intent.
The blockchain has the potential to get back to the promise of the internet and usher in a new era of distributed applications with security and resiliency at their core.
For many things such as clothing, furniture, building materials and more, you’ll choose a template online and print it out.
Once the speed is faster, we will have more applications and hardware connected to the internet.
Could we dream of Netflix streaming in 2001 when the internet was slow? Speed will be the king.
The views expressed are the author’s own and not necessarily shared by TNW. Read next: Google is reportedly building hardware for its game streaming service.

The orginal article.

Summary of “How close are LeBron James, Los Angeles Lakers to winning a title?”

LeBron James is headed to the Los Angeles Lakers, with or without another superstar alongside him.
The timing of James’ announcement that he has agreed to a four-year, maximum deal with the Lakers – including a player option in the final year – a day after Paul George and Chris Paul reportedly agreed to re-sign with their current teams suggests that this decision wasn’t necessarily about the players he’ll join in L.A. With James electing to sign a long-term deal rather than playing year to year, as he did after returning to the Cleveland Cavaliers four years ago, it further indicates that he is in this for the long haul rather than focused on challenging the Golden State Warriors right away.
Still, the whole purpose of signing James is building the Lakers back into a championship contender.
Though James seems largely impervious to the effects of aging, at 33 there is urgency for the Lakers to get there sooner rather than later.
The Lakers could still get up to $16-plus million in cap space by waiving forward Luol Deng, while stretching the remaining two years on his contract would get the Lakers to nearly $25 million in cap room.
Will the Lakers add another star in 2019?The scenario I’ve outlined where the Lakers sign nothing but one-year deals this summer would leave L.A. with something like $25 million in cap space in 2019 with Deng on the books.
Let’s take an early stab at what we can expect from the Lakers with LeBron utilizing projections based on the multi-year, predictive version of ESPN’s real plus-minus.
The Lakers don’t likely have a path to challenging the Warriors next season, even with James.

The orginal article.

Summary of “Don’t Hate the Warriors, Hate the System That Allowed Them to Happen”

The Golden State Warriors are what they are today largely because of a decision made by the National Basketball Players Association more than three years ago.
Then the salary cap spiked from $70 million in 2015-16 to $94.1 million in 2016-17, which allowed the Warriors to sign Kevin Durant while giving up only Andrew Bogut and their rights to Harrison Barnes.
The ramifications of the decision linger today; in fact, it’s what helped allow the Warriors to lock in DeMarcus Cousins on Monday night.
The Warriors have gotten much, much richer as a result, but that hasn’t been the case throughout the league.
If close to healthy, Cousins will help the Warriors as a scoring weapon and post passer.
The NBA can install a hard cap to try to prevent another superteam as strong as the Warriors, but it’d need to get creative to stop a superpower from taking advantage of an opportunity like the Warriors did with Cousins.
I’m excited for a team to try to push the juggernaut Warriors to their limits.
The Warriors will break up at some point, because of the luxury tax or boredom, but Silver and the NBA would be wise to continue pushing for proactive measures whenever the next collective bargaining negotiations come around.

The orginal article.

Summary of “Alexandria Ocasio-Cortez’s Message to the Democratic Party”

After winning the Democratic primary in New York’s Fourteenth Congressional District, Alexandria Ocasio-Cortez is now a national political figure.
She delivered an important message to the Democratic Party by running an explicitly populist, anti-establishment campaign.
“He spoke very directly to a lot of needs that were not being met by both the Democratic Party and the Republican Party,” she told the Intercept’s Glenn Greenwald.
Ocasio-Cortez’s second point is related to the first: to attract working-class and middle-class voters of all colors and ethnicities, Democratic candidates need to demonstrate that they aren’t part of a system rigged in favor of the rich and powerful.
As a former campaign organizer for Bernie Sanders, Ocasio-Cortez levelled many of the same charges against her opponent, the ten-term Democratic congressman Joseph Crowley, that Sanders hurled at Hillary Clinton during the 2016 Democratic primary.
To position itself as a truly populist force, Ocasio-Cortez says, the Democratic Party must make a decisive leap from the standard methods of financing campaigns through corporate-money politics-and from the conflicts of interest that come with them.
With the Democratic Party preparing to fight elections against opponents financed by the likes of Sheldon Adelson and the Koch brothers, many more seasoned Democrats would say that Ocasio-Cortez is being unrealistic, that the Party has no choice but to accept big donations from people like Tom Steyer, George Soros, and Michael Bloomberg.
Alexandria Ocasio-Cortez just demonstrated how to do this.

The orginal article.

Summary of “The treasure hunters on a deadly quest for an eccentric’s $2m bounty”

The pair had come to this starkly beautiful place, at the base of the Sangre De Cristo mountains, to hunt for a treasure rumored to be worth upwards of $2m. Johnston, a 37-year-old real estate agent from Albuquerque, had invited the Guardian along on a search for a 10in-by-10in box of gems, gold, cash and precious antiquities that an eccentric millionaire named Forrest Fenn says he hid somewhere in the Rocky Mountains in 2009.
The idea of hiding a treasure came to Fenn in 1988 after he was diagnosed with an aggressive form of kidney cancer.
For others, Fenn’s treasure has endowed their lives with a profound sense of meaning and direction.
In September 2016, Randy wrote Fenn an email with the line: “I will find your treasure or die trying.” Four months later, he went missing after trying to cross the Rio Grande in a small raft he bought at a sporting goods store.
In June 2017, an Illinois man named Jeff Murphy fell 500ft to his death while hunting for Fenn’s treasure in Yellowstone national park.
Asked about the deaths, Fenn replied: “Of course it’s very tragic. But every time you get in a car you put yourself at risk.” He has long stressed that the treasure is not in a dangerous or hard-to-reach place.
While the response to the treasure has been intense, it has also been of Fenn’s own making.
A few minutes after he sat down with a reporter recently, an erratic-sounding and increasingly emotional man called Fenn to say that he was convinced he was close to the treasure.

The orginal article.

Summary of “Aztec moral philosophy didn’t expect anyone to be a saint”

While Plato and Aristotle were concerned with character-centred virtue ethics, the Aztec approach is perhaps better described as socially-centred virtue ethics.
One of the advantages of the Aztec view is that it avoids this outcome by casting virtue as a cooperative, rather than an individual, endeavour.
At its core, Aztec virtue ethics has three main elements.
To explain the Aztec conception of the good life, it’s helpful to begin in the sixth volume of a book called the Florentine Codex, compiled by Father Bernardino of SahagĂșn.
The passage is striking because it highlights a fundamental difference between the Ancient Greek and the Aztec approaches to the good life – namely, that the Aztecs did not believe there was any conceptual link between leading our best lives on the one hand, and experiencing pleasure or ‘happiness’ on the other.
‘ The Aztecs held, in short, that it’s unrealistic to think that anyone can lead a perfectly good life, one in which you never slip up.
Public drunkenness was severely punished in Tenochtitlan, the capital of the Aztec empire; for nobles, the penalty was death.
How we develop this understanding of virtuous action leads us to the final pillar of Aztec ethics.

The orginal article.

Summary of “Threat Perception: Why Our Brains Constantly Perceive New Risks”

Do many problems in life seem to stubbornly stick around, no matter how hard people work to fix them? It turns out that a quirk in the way human brains process information means that when something becomes rare, we sometimes see it in more places than ever.
To study how concepts change when they become less common, we brought volunteers into our laboratory and gave them a simple task – to look at a series of computer-generated faces and decide which ones seem “Threatening.” The faces had been carefully designed by researchers to range from very intimidating to very harmless.
As we showed people fewer and fewer threatening faces over time, we found that they expanded their definition of “Threatening” to include a wider range of faces.
In other words, when they ran out of threatening faces to find, they started calling faces threatening that they used to call harmless.
Why can’t people help but expand what they call threatening when threats become rare? Research from cognitive psychology and neuroscience suggests that this kind of behavior is a consequence of the basic way that our brains process information – we are constantly comparing what is front of us to its recent context.
Instead of carefully deciding how threatening a face is compared to all other faces, the brain can just store how threatening it is compared to other faces it has seen recently, or compare it to some average of recently seen faces, or the most and least threatening faces it has seen.
This kind of comparison could lead directly to the pattern my research group saw in our experiments, because when threatening faces are rare, new faces would be judged relative to mostly harmless faces.
In a sea of mild faces, even slightly threatening faces might seem scary.

The orginal article.

Summary of “The Psychology of MoviePass Outrage, or: Why Is My Consumer Brain So Dumb?”

My annoyance with the app began when MoviePass surreptitiously removed major AMC locations from its service as a strategic bargaining move against the theater chain.
As you might expect, my growing bitterness toward MoviePass is shared by the millions of other people who subscribed to the service in the past year.
“I am a loyal Moviepass subscriber, and today I registered for AMC A-List,” one Redditor, who is referring to AMC’s new, competing Stubs A-List service, wrote.
“NOT because I support AMC, but because, on a basic level: I want to pay money in exchange for a stable service without having to wonder if the company will process my payment and then reduce the service, without having to hope that the service will actually function on a given day, and without having to frustrate myself when the company refuses to provide any avenue for meaningful customer support over a prolonged period of time.” Others have simply declared MoviePass a scam.
The ironic subtext to all of this consumer anger, including mine, is that despite all the drama, both MoviePass and Stub A-List are objectively great deals.
Most modern subscription apps function on a flat-fee model, in which a consumer pays a lump sum every month for mostly unfettered access to something like a gym, rental equipment, or a telephone service.
Kolenda points to a 2000 study by Joseph C. Nunes that presented participants with hypothetical flat-fee deals versus pay-as-you-go options for services like online grocery delivery services and monthly pool access.
“No consumer likes a higher price. The challenge that the company faces is how to make the process as painless as possible. Most companies find ways to reduce the pain, but MoviePass just can’t seem to make the pain go away.” If this darling startup wants us along for the ride, they at least have to promise the wheels won’t fall off.

The orginal article.